Thrombocytopenia can be inherited, acquired through lifestyle factors over time (such as poor diet combined with alcohol) or brought on by medicines or infections. Symptoms were similar to getting the Flu Shot. This mutation can increase your chance of developing abnormal As such, whole viral particles are never produced during vaccine processing. On the other hand, critically ill patients with COVID-19 and low levels of factor V appear to be at increased risk for death from a form of coagulopathy that resembles disseminated intravascular coagulation (DIC)a devastating, often fatal abnormality in which blood clots form in small vessels throughout the body, leading to exhaustion of clotting factors and proteins that control coagulation. PRIMARY SERIES Can you mix the vaccines for your mRNA primary vaccination series? For thosewith pre-existing ITP (even if you dont take medicine for your ITP and even if your platelet count is normal), consult your hematologist and obtain a platelet count prior to vaccination. The prevalence of Pulmonary Embolism, in particular was 3.5% in both non-ICU and ICU patients. At the time, more than 8 million doses had been administreted (15/8,000,000 is a rate of .0001875% - that is less than a 2 ten-thousandths risk). I still think about how close I felt to death. At least 4 weeks after 1st dose and should be Pfizer-BioNTech or Moderna, Pfizer-BioNTech or Moderna Their findings are: - Incidence of CVT after COVID diagnosis was 42.8 per million, including 35.3 per million first diagnosis. Can you share the research you looked at on risk of clots from Covid vs. vaccine? In all, 33 percent of patients with factor V activity well above the reference range had either deep vein thrombosis or a pulmonary embolism, compared with only 13 percent of patients with lower levels. It is definitely a difficult decision when we don't have all the information, however, at this point, it has been 10 days since I got my vaccine - I feel great so far! In all, 33 percent of patients with factor V activity well above the reference range had either deep vein thrombosis or a pulmonary embolism, compared with only 13 percent of patients with lower levels. The Pfizer-BioNTech COVID-19 Vaccine received emergency use authorization (EUA) on December 11, 2020 for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 16 years of age and older. PRIMARY SERIES I am a healthy 57 year old breast cancer survivor (6 years) with factor V Leiden. I met with both my GP and my Hematologist last week about my concerns about the vaccine and both felt it was better to do than not, as I work in a Hotspot in Ontario, Canada. The Janssen Biotech vaccine contains a type of a human adenovirus. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. However, if the mRNA vaccine product given for the first two doses is not available or is unknown, either Pfizer-BioNTech or Moderna COVID-19 vaccine (mRNA COVID-19 vaccines) may be administered for the third primary dose. Their findings, based on studies of patients with COVID-19 in Mass General intensive care units (ICUs), point to disturbances in factor V activity as both a potential cause of blood clotting disorders with COVID-19, and to potential methods for identifying at-risk patients with the goal of selecting the proper anticoagulation therapy. The vaccine contains a nucleoside-modified messenger RNA (modRNA) encoding the viral spike (S) glycoprotein of SARS-CoV-2 formulated in lipid particles. 6. These dissolved proteins are called clotting factors, and some of the ingredients in contraceptives increase the levels of certain clotting factors in the blood, which raises the odds of clots forming in veins. I have Factor V Leiden homozygous as well. Individuals who are pregnant and considering vaccination for COVID-19 are encouraged to speak with their clinicians. I am also hetero factor V leiden. or risk of disease in a loved one or close contact. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Some vaccines must be administered using the accompanying needlesyringe combination, and so the use of an alternative needle may not be possible or desirable. Since factor V Leiden is a risk for developing blood clots in the leg or lungs, the first indication that you have the disorder may be the development of an abnormal blood clot. Because people with bleeding disorders are not at a greater risk of contracting COVID-19 or developing a severe form of the disease, they are generally not considered a priority group. I got the Pfizer vaccine three days ago and after reading this I think my BP just shot uplol. I agree with everything you said. Im glad you are choosing a modest serving size for your evening glass. Despite the combined oral contraceptive pill also increasing the risk of blood clots in those who take it, these clots are likely formed by a different mechanism to those seen in CVSTs. UPDATED BOOSTER Accompanying symptoms include headache, tiny red spots under the skin, blurred vision, fainting or loss of consciousness, loss of movement in parts of the body, or coma. If you have a bleeding disorder, there are no contraindications to being vaccinated with any of the three vaccines now available via EUA status for intramuscular administration. 2. I have had both Pfizer vaccines without any issues. The vaccine should be administered intramuscularly. The vaccine does not contain a preservative. However, certain factors could be reasons to get a vaccine sooner rather than later, such as: To receive email updates about COVID-19, enter your email address: We take your privacy seriously. All three vaccines are designed to tell your body how to make the Spike protein, part of the SARS-CoV-2 virus. Following an extensive evidence review, the American College of Obstetricians and Gynecologists recommends that COVID-19 vaccines should not be withheld from pregnant individuals. Additional resources Thrombosis - Clot Connect: http://www.clotconnect.org/ Thrombosis - Stop The Clot: At least 2 months after 3rd dose, Pfizer-BioNTech or Moderna //-->